Molecular Networks in Medical Bioinformatics

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Dr. Mario Albrecht

Biological networks are in the center of many life’s processes and involved in essential tasks of cells in organisms. To gain insight into the complex processes, the research group directed by Dr. Mario Albrecht devises new bioinformatics methods and applies them to genome-wide datasets. This computational approach helps to analyze molecular interaction networks and to improve their understanding. The scientists are particularly interested in signaling processes that are disturbed in important diseases such as chronic inflammations and virus infections. Thus, bioinformatics methods support the discovery of novel disease genes and the development of computer models for diseases and drug effects.

Our projects

Standard therapies against viral infections are often not as effective as desired. Frequently, they also cause unwanted side effects for patients. Thus, biomedical researchers apply new molecular technologies to reveal the cellular disease processes and to find novel drug targets. To this end, innovative bioinformatics approaches are required to mine the ever-growing, huge amounts of molecular data. Therefore, new network-based methods are developed to identify the human genes and their interactions that are relevant to the viral life cycle in human cells. This work leads to new therapeutic options for patients and improves the individual diagnosis and treatments of infectious diseases.